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Experiment

Akt1;Akt2;Foxo1 TKO clamp

Summary

Data Summary

Investigator	Shulman, Gerald I.
Description	Applicable research area(s): Diabetes, Obesity, Metabolism
Status	Completed
Public Release	6/23/2018
Data Collected?	Data will not be collected for this catalog item
Animal Age	Measured In: week(s) post-natal (w)
Flags

Data Analysis

DOWNLOAD ALL DATA (.csv)

Type	Count
Animals	24
Experimental Conditions	2
Catalog Items	1
Curation Info (# flags)	2
Phenotype Assays	13
Phenotype Measurements	312
Histology Images	0
Publications	0

Animals

Strain Name	Common Name	Females	Males	Unknown
C57BL/6	C57BL/6	0	12	0
B6.129-Akt1^tm2Mbb Akt2^tm1Mbb Foxo1^tm2.1Dac Tg(Nes-cre)1Kln Tg(Alb1-cre)1Khk Tg(Serpina1-Cre)	Akt1^loxP/loxP Akt2^loxP/loxP Foxo1^loxP/loxP Tg(Nes-Cre) Tg(Alb-Cre) Tg(Serpina1-Cre)	0	12	0

Animals/Strains

Experimental Factors

	Categorical Values
	Name / Abbreviation	Description
	Experimental Factor: Drug Administered
	Acetate-Glycerol	Animals received both Acetate and Glycerol
	No Drug/Treatment	No Drug or Treatment done on these samples
	Experimental Factor: Experimental Group
	Control	This animal belongs to the control group for the experiment.
	Experiment	This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor (Units)
Drug Administered
Experimental Group

Experimental Factor Values

Phenotype Assays Add / Edit

Name	Abbreviation
glucose uptake	glucose uptake
average clamp glucose	average clamp glucose
fat body mass	fat body mass
lean body mass	lean body mass
total body weight	total body weight
glucose, basal	glucose, basal
hepatic glucose production, basal	hepatic glucose production, basal
glucose synthesis	glucose synthesis
glucose turnover, whole body	glucose turnover, whole body
glycogen/lipid synthesis, whole body	glycogen/lipid synthesis, whole body
glycolysis, whole body	glycolysis, whole body
glycogen synthesis	glycogen synthesis
glycolysis	glycolysis

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