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Experiment

Liver TG and TC levels in FGF-21 treated C57 mice
Summary Data Summary
Investigator Ryan, Karen
Description 38 mice (19 males, 19 females) were administered twice daily IP injections of
0.1mg/kg FGF21. Daily body weight and food intake was monitored. A day 0 and Day
10 NMR and GTT was performed

Applicable research area(s): Obesity, Metabolism
Status Completed
Public Release 8/26/2018
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainExperiment Description
Data Analysis
TypeCount
Animals36
Experimental Conditions8
Catalog Items3
Curation Info (# flags)2
Phenotype Assays2
Phenotype Measurements72
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6J
18
18
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Administered

 FGF-21
Fibroblast growth factor 21 is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family and specifically a member of the "endocrine" subfamily which includes...
 Saline
Saline

Experimental Factor: Drug Dose (AU)

 Drug Dose
A numerical value indicating the dose of a drug administered. The unit of measure is indicated in the Drug Dose Units categorical value that accompanies this experimental condition.

Experimental Factor: Drug Dose Units

 mg/kg/d
milligrams per kilograms per day

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Fast Duration (hr)

 fast duration
Length of time the animal was fasted

Experimental Factor: Feeding Group

 Fasted
Animals are deprived of food but not water.

Experimental Factor: Mouse Diet

 LabDiet 5008
crude protein (23.0%), crude fat (6.5%), crude fiber (4.0%), Ash (< 8.0%), minerals (2.5%)

Experimental Factor: Tissue Source

 liver
liver


Phenotype Assays Add / Edit


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