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Experiment

Circulating FFA and glycerol levels in B6 mice treated with FGF-21
Summary Data Summary
Investigator Ryan, Karen
Description 38 mice (19 males, 19 females) were administered twice daily IP injections of
0.1mg/kg FGF21. Daily body weight and food intake was monitored. A day 0 and Day
7 NMR and day 0 and 10 GTT was performed.

Applicable research area(s): Diabetes, Metabolism, Obesity
Status Completed
Public Release 2/7/2019
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainExperiment Description
Data Analysis
TypeCount
Animals72
Experimental Conditions8
Catalog Items1
Curation Info (# flags)2
Phenotype Assays2
Phenotype Measurements72
Histology Images0
Publications0
Phenotypes1


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6J
36
36
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Administered

 FGF-21
Fibroblast growth factor 21 is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family and specifically a member of the "endocrine" subfamily which includes...
 Saline
Saline

Experimental Factor: Drug Dose Units

 mg/kg/d
milligrams per kilograms per day

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Feeding Group

 Fasted
Animals are deprived of food but not water.

Experimental Factor: Mouse Diet

 Research Diets - D12492
Rodent Diet with 34% Fat, 60% kcal from Fat

Experimental Factor: Tissue Source

 plasma (EDTA)
plasma (EDTA)
Experimental Factor Values


Phenotype Assays Add / Edit


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