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Experiment

Circulating insulin levels in B6 mice treated with niclosamide
Summary Data Summary
Investigator Shengkan, Jin
Description We had the C57BL6/J mice randomized into groups. These mice were all fed on
high-fat diet (the Research Diets Inc. D12492) for 12 weeks. Group 1 is controls
without any treatment, including mice C1-C8. Group 2 is niclosamide treatment
group with oral treatment of niclosamide mixed into chow 1500ppm

Applicable research area(s): Diabetes, Endocrine deficiency, Metabolism
Status Completed
Public Release 11/15/2018
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame Strain
Data Analysis
TypeCount
Animals16
Experimental Conditions5
Catalog Items1
Curation Info (# flags)1
Phenotype Assays1
Phenotype Measurements16
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6J
0
16
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Feeding Group

 Fasted
Animals are deprived of food but not water.

Experimental Factor: Mouse Diet

 Research Diets - D12492
Rodent Diet with 34% Fat, 60% kcal from Fat
 Research Diets - D12492 1500 ppm NEN
Rodent Diet with 60% fat, 20% carbohydrate, 20% protein supplemented with 1500 ppm niclosamide ethanolamine (NEN)

Experimental Factor: Tissue Source

 plasma (EDTA)
plasma (EDTA)
Experimental Factor Values


Phenotype Assays Add / Edit


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