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Experiment

Liver TC and TG levels in B6 mice treated with FGF21
Summary Data Summary
Investigator Ryan, Karen
Description Observe metabolic response to chronic FGF-21 injection or protein restriction.

76 mice (males, females (intact and OVX)) were fed a HFD prior twice daily IP
injections of 0.1mg/kg FGF21.
Status Completed
Public Release 11/15/2018
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainExperiment Description
Data Analysis
TypeCount
Animals76
Experimental Conditions8
Catalog Items2
Curation Info (# flags)2
Phenotype Assays2
Phenotype Measurements152
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6J
50
26
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Administered

 FGF-21
Fibroblast growth factor 21 is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family and specifically a member of the "endocrine" subfamily which includes...
 Vehicle
Vehicle - Control

Experimental Factor: Drug Dose (AU)

 Drug Dose
A numerical value indicating the dose of a drug administered. The unit of measure is indicated in the Drug Dose Units categorical value that accompanies this experimental condition.

Experimental Factor: Drug Dose Units

 mg/kg/d
milligrams per kilograms per day

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Fast Duration (hr)

 fast duration
Length of time the animal was fasted

Experimental Factor: Feeding Group

 Fed
Animals are allowed to have food.

Experimental Factor: Mouse Diet

 Research Diets - D12492
Rodent Diet with 34% Fat, 60% kcal from Fat

Experimental Factor: Tissue Source

 liver
liver


Phenotype Assays Add / Edit


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