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Experiment

Metabolic measurements in p65Schc -/- mice
Summary Data Summary
Investigator Ramsey, Jon
Description It has been proposed that p66Shc-/- mice are resistant to weight gain with high
fat feeding. This mice are also resistant to wide range of stress inducers.

Calorimetry measurements will be completed over 7 days. The mice will be fed a
chow diet for the first 2 days of calorimetry and a high fat diet (60% of
calories from fat) for the final 5 days of calorimetry.

Applicable research area(s): Diabetes, Obesity, Metabolism
Status Completed
Public Release 2/28/2019
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagAnimal Count
Data Analysis
TypeCount
Animals14
Experimental Conditions2
Catalog Items2
Curation Info (# flags)1
Phenotype Assays31
Phenotype Measurements868
Histology Images0
Publications0
Documents2
Phenotypes2


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6J
0
7
0
C57BL/6J-p66Shc1-/-
0
7
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 JJR_CONTROL
based on AIN93G; caloric density=3.95 kcal/g
 JJR_HFD
based on TD.06414 60.3% fat, 18.3% protein, 21.4% carbohydrate); caloric density=5.1 kcal/g. Lard 4.650 kg, Casein 3.975 kg, Dextrine 2.400 kg, Sucrose 1.350 kg, Cellulose 0.983 kg, AIN-93G-MX Min Mx 0.720 kg, Soy Oil 0.450 kg, Calcium Phosphate,...



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