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Experiment

Liver TG and TC levels in C57 mice treated with FGF-19
Summary Data Summary
Investigator Ding, Xunshan
Description To determine mouse liver triglyceride and cholesterol content: 8-month old DIO
mice from Jax were treated with a biweekly 10mg/kg IP dose of FGF19 analog for 3
weeks before terminated using carbon dioxide. Liver samples were collected and
snap frozen and kept at -80C.

Applicable research areas: Metabolic syndrome, Diabetes, Obesity
Status Completed
Public Release 2/2/2019
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagExperiment / ControlExperiment Description
Data Analysis
TypeCount
Animals85
Experimental Conditions8
Catalog Items2
Curation Info (# flags)2
Phenotype Assays2
Phenotype Measurements170
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6
0
28
0
BKS db
0
57
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Administered

 FGF-19
Fibroblast growth factor 19 is a protein that in humans is encoded by the FGF19 gene. It functions as a hormone, regulating bile acid synthesis, with effects on glucose and lipid metabolism

Experimental Factor: Drug Dose Units

 mg/kg biweekly
milligrams per kilogram every other week

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Feeding Group

 Fed
Animals are allowed to have food.

Experimental Factor: Mouse Diet

 Research Diets - D12492
Rodent Diet with 34% Fat, 60% kcal from Fat

Experimental Factor: Tissue Source

 liver
liver
Experimental Factor Values


Phenotype Assays Add / Edit


No documents found.

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