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Experiment

Comprehensive Analysis on the Metabolic Effects of Brown Adipose-Specific
Deletion of Fatty Acid Synthase
Summary Data Summary
Investigator Czech, Michael
Description This study will involve 4 UCP1-FASN KO mice and 4 WT mice. The Metabolism Core
studies will involve the following:

Energy balance measurement using TSE Metabolic Cages, Blood sampling for
Analytical Core studies, and In vivo lipid uptake measurement in brown adipose
tissue.

The Analytical Core studies will involve multiplexed-analysis using Cobas
Clinical Chemistry Analyzer for serum levels of TG, NEFA, and Cholesterol
(total, HDL, LDL).

Applicable research area(s): Diabetes, Obesity, Metabolism
Status PhenStat Analysis Verified
Public Release 11/4/2019
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainNomenclature
Data Analysis
TypeCount
Animals17
Experimental Conditions1
Catalog Items10
Curation Info (# flags)2
Phenotype Assays4
Phenotype Measurements68
Histology Images0
Publications0
Phenotypes2


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6
0
8
0
Ucp1-cre Fasn KO
0
9
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.
Experimental Factor (Units)
Experimental Group
Experimental Factor Values


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