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Experiment

Circulating insulin levels following glucose gavage in liver specific Esr1 KO
mice fed high fat diet
Summary Data Summary
Investigator Ingraham, Holly
Description Experiment details (This is essential information to be provided by
investigator). Group one: 21-23 week old male and female mice placed on a high
fat diet (Research Diets 12492) for 8 weeks Mice were fasted for 6 hours prior
to collecting serum via submandible punture and then were gavaged with 1g/kg of
dextrose and sample collected at 15 minutes

Applicable research area(s): Metabolism, Obesity
Status Completed
Public Release 4/6/2020
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagAnimal CountNeed Conditions
Data Analysis
TypeCount
Animals14
Experimental Conditions8
Catalog Items3
Curation Info (# flags)2
Phenotype Assays3
Phenotype Measurements84
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
Esr1 LKO
7
7
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Delivery Route

 PO
The drug was delivered orally

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Feeding Group

 Fasted
Animals are deprived of food but not water.
 Fed
Animals are allowed to have food.

Experimental Factor: Mouse Diet

 Research Diets - D12492
Rodent Diet with 34% Fat, 60% kcal from Fat

Experimental Factor: Tissue Source

 serum
serum
Experimental Factor Values


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