MMPC :: Phenotype Assay

Phenotype Assay

alanine aminotransferase (ALT)
units per liter (U/L)

Name	alanine aminotransferase
Abbreviation	ALT
Is Categorical?	False
Tissue(s)	blood, liver
Group(s)	enzymes
Description	Alanine transaminase (ALT) is a transaminase enzyme (EC 2.6.1.2). ALT is found in plasma and in various body tissues, but is most common in the liver. It catalyzes the two parts of the alanine cycle. Serum ALT level, serum AST (aspartate transaminase) lev
Protocol	Not Specified

Display Stats

OrderID	Order	Investigator	Experiment	Status	Measurements
30450	30450	Claudia Rodrigues	Circulating ALT, AST levels in Myc KO mice fed high fat and high cholesterol diet	Completed	74
30407	30407	Claudia Rodrigues	Circulating lipid levels and ALT, AST levels in Myc KO mice fed high fat and high cholesterol diet	Completed	185
21765	21765	Pei-Yu Chen	4M WT atherosclerosis	Completed	70
30358	30358	Jin Shengkan	Circulating ALT, and AST levels in B6 mice treated with derivatives of niclosamide and CCL4	Completed	104
30412	30412	Jin Shengkan	Circulating lipid, insulin, ALT and AST levels in Lepr KO mice treated with derivatives of niclosamide	Completed	384
20735	20735	Pei-Yu Chen	TGFb signaling in atherosclerosis.	Completed	200
22469	22469	Holly Ingraham	Circulating insulin levels following glucose gavage in liver specific Esr1 KO mice fed high fat diet	Completed	84
21864	21864	Jin Shengkan	Metabolic measurements in B6 mice treated with metformin and niclosamide	Completed	96
25612	25612	Jin Shengkan	Circulating albumin, ALT, and AST levels in B6 mice treated with niclosamide and CCL4	Completed	120
25562	25562	Jin Shengkan	Circulating insulin, lipid, ALT, and AST levels in B6 mice treated with niclosamide	Completed	33
20732	20732	Noemi Rotllan Vila	Influence of the treatment with miR-148a LNA on hepatic lipid metabolism	Completed	96
22338	22338	Jin Shengkan	Circulating insulin, lipid, ALT, and AST levels in B6 mice fed high fat diet and treated with niclosamide	Completed	126
22232	22232	Holly Ingraham	Circulating ALT levels in liver specific Nr5a2 KO mice treated with AAV8-Lrh1	Completed	24
18586	18586	Jin Shengkan	Metabolic measurements in B6 mice fed high fat diet and treated with fruit extracts	Completed	90
22299	22299	Holly Ingraham	Circulating ALT and FFA levels in liver specific Nr5a2 KO mice Part 2	Completed	24
21818	21818	Holly Ingraham	Circulating ALT and FFA levels in liver specific Nr5a2 KO mice	Completed	38
22167	22167	Holly Ingraham	Circulating ALT and FFA levels in liver specific Esr1 KO mice	Completed	58
22108	22108	Jin Shengkan	Circulating cytokine levels in B6 mice treated with NEN, metformin, and cholestyramine	Completed	351
18566	18566	Noreene Shibata	Circulating ALT levels in tx-J mice Part 3	Completed	74
14366	14366	Noreene Shibata	Circulating ALT levels in tx-J mice part 2	Completed	32
13239	13239	Noreene Shibata	Circulating ALT levels in tx-J mice	Completed	45
21832	21832	Jin Shengkan	Metabolic measurements in ApoE KO mice treated with metformin and niclosamide pt2	Completed	360
21813	21813	Jin Shengkan	Metabolic measurements in ApoE KO mice treated with metformin and niclosamide	Completed	225
20734	20734	SHI-YING CAI	Testing CVC+RA in cholestatic liver injury.	Completed	96
20724	20724	Jin Shengkan	Metabolic measurements in Lipa KO mice treated with niclosamide	Completed	98
2525	2525	SHI-YING CAI	Cobas Order # 2525	Completed	36
18583	18583	Anand Narayanan	Pathophysiology of metabolism and atherosclerosis 2	Completed	72
18513	18513	Anand Narayanan	lipid profile in blood in TCF7l2 of over-expression	Completed	55
18468	18468	Anand Narayanan	Pathophysiology of metabolism and atherosclerosis	Completed	78
11003	11003	Valentina Medici	Circulating ALT and AST levels in tx-J KO mice	Completed	173
2432	2432	SHI-YING CAI	Cobas Order # 2432	Completed	88
1621	1621	Romina Fiorotto	Notch2 is required for proper IHBD development and morphogenesis.	Completed	111
2527	2527	SHI-YING CAI	Cobas Order # 2527	Completed	68
12009	12009	Man Li	ManLi.12009	Completed	62
10938	10938	SHI-YING CAI	ShiYing.10938	Completed	56
21841	21841	SHI-YING CAI	Examine Tlr9's role in cholestatic liver injury	Completed	44
21754	21754	Jessica Costa	Liver-specific loss of Hrpt2	Completed	234
19692	19692	SHI-YING CAI	Measure plasma liver enzyme activity.	Completed	52
18460	18460	Leigh Goedeke	Influence of miR-148a on hepatic lipid metabolism	Completed	79
19633	19633	Anand Narayanan	Determine lipid profiles in blood in TCF7l2 overexpression mice on chow diet (8 months)	Completed	66
18531	18531	Yen Hao Chen	mice liver and kidney function	Completed	45
21849	21849	David Assis	OVA-BIL Receiving OT1/OT2 part 2	Completed	22
19695	19695	David Assis	OVA-HEP Thy1.1 Receiving OT1/OT2 vs WT	Completed	8
19636	19636	SHI-YING CAI	Cholecystectomy in Mdr2 knockout mice to assess liver injury in this cholestatic model.	Completed	54
13311	13311	David Assis	Evaluation of concanavalin A induced hepatitis.	Completed	26
13326	13326	Tomas Majtan	Effect of PEG-CBS ERT on liver function of the I278T homocystinuria mouse model	Completed	40
10977	10977	Carol Soroka	CarolSoroka.10977	Completed	11
10866	10866	Saleh Rachidi	SalehRachidi.10866	Completed	74
2383	2383	SHI-YING CAI	Cobas Order # 2383	In Progress	88
2253	2253	Huricha Baigude	Cobas 6/15/11	Completed	0

Associated MP Terms

MP:0001573 - abnormal circulating alanine transaminase level
MP:0002941 - increased circulating alanine transaminase level
MP:0002942 - decreased circulating alanine transaminase level

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