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Phenotype Assay
alanine aminotransferase (ALT)
units per liter (U/L)

Name alanine aminotransferase
Abbreviation ALT
Is Categorical? False
Tissue(s) blood, liver
Group(s) enzymes
Description Alanine transaminase (ALT) is a transaminase enzyme (EC 2.6.1.2). ALT is found
in plasma and in various body tissues, but is most common in the liver. It
catalyzes the two parts of the alanine cycle. Serum ALT level, serum AST
(aspartate transaminase) lev
Protocol Not Specified

Experiments
OrderInvestigatorExperimentStatusMeasurements
11003Valentina Medici
Circulating ALT and AST levels in tx-J KO mice
Completed173
14366Noreene Shibata
Circulating ALT levels in tx-J mice part 2
Completed32
13239Noreene Shibata
Circulating ALT levels in tx-J mice
Completed45
18513Anand Narayanan
lipid profile in blood in TCF7l2 of over-expression
Completed55
18468Anand Narayanan
Pathophysiology of metabolism and atherosclerosis
Completed78
18583Anand Narayanan
Pathophysiology of metabolism and atherosclerosis 2
Completed72
10938SHI-YING CAI
ShiYing.10938
Completed56
18460Leigh Goedeke
Influence of miR-148a on hepatic lipid metabolism
Completed79
2383SHI-YING CAI
Cobas Order # 2383
In Progress88
10866Saleh Rachidi
SalehRachidi.10866
Completed74
10977Carol Soroka
CarolSoroka.10977
Completed11
30450Claudia Rodrigues
Circulating ALT, AST levels in Myc KO mice fed high fat and high cholesterol diet
Completed74
20732Noemi Rotllan Vila
Influence of the treatment with miR-148a LNA on hepatic lipid metabolism
Completed96
20735Pei-Yu Chen
TGFb signaling in atherosclerosis.
Completed200
22108Jin Shengkan
Circulating cytokine levels in B6 mice treated with NEN, metformin, and cholestyramine
Completed351
19636SHI-YING CAI
Cholecystectomy in Mdr2 knockout mice to assess liver injury in this cholestatic model.
Completed54
19633Anand Narayanan
Determine lipid profiles in blood in TCF7l2 overexpression mice on chow diet (8 months)
Completed66
19692SHI-YING CAI
Measure plasma liver enzyme activity.
Completed52
19695David Assis
OVA-HEP Thy1.1 Receiving OT1/OT2 vs WT
Completed8
2432SHI-YING CAI
Cobas Order # 2432
Completed88
12009Man Li
ManLi.12009
Completed62
13326Tomas Majtan
Effect of PEG-CBS ERT on liver function of the I278T homocystinuria mouse model
Completed40
13311David Assis
Evaluation of concanavalin A induced hepatitis.
Completed26
30358Jin Shengkan
Circulating ALT, and AST levels in B6 mice treated with derivatives of niclosamide and CCL4
Completed104
30407Claudia Rodrigues
Circulating lipid levels and ALT, AST levels in Myc KO mice fed high fat and high cholesterol diet
Completed185
30412Jin Shengkan
Circulating lipid, insulin, ALT and AST levels in Lepr KO mice treated with derivatives of niclosamide
Completed384
21765Pei-Yu Chen
4M WT atherosclerosis
Completed70
22469Holly Ingraham
Circulating insulin levels following glucose gavage in liver specific Esr1 KO mice fed high fat diet
Completed84
25562Jin Shengkan
Circulating insulin, lipid, ALT, and AST levels in B6 mice treated with niclosamide
Completed33
1621Romina Fiorotto
Notch2 is required for proper IHBD development and morphogenesis.
Completed111
2525SHI-YING CAI
Cobas Order # 2525
Completed36
2527SHI-YING CAI
Cobas Order # 2527
Completed68
21754Jessica Costa
Liver-specific loss of Hrpt2
Completed234
20724Jin Shengkan
Metabolic measurements in Lipa KO mice treated with niclosamide
Completed98
21818Holly Ingraham
Circulating ALT and FFA levels in liver specific Nr5a2 KO mice
Completed38
21813Jin Shengkan
Metabolic measurements in ApoE KO mice treated with metformin and niclosamide
Completed225
21832Jin Shengkan
Metabolic measurements in ApoE KO mice treated with metformin and niclosamide pt2
Completed360
21864Jin Shengkan
Metabolic measurements in B6 mice treated with metformin and niclosamide
Completed96
25612Jin Shengkan
Circulating albumin, ALT, and AST levels in B6 mice treated with niclosamide and CCL4
Completed120
21841SHI-YING CAI
Examine Tlr9's role in cholestatic liver injury
Completed44
21849David Assis
OVA-BIL Receiving OT1/OT2 part 2
Completed22
18531Yen Hao Chen
mice liver and kidney function
Completed45
2253Huricha Baigude
Cobas 6/15/11
Completed0
20734SHI-YING CAI
Testing CVC+RA in cholestatic liver injury.
Completed96
18566Noreene Shibata
Circulating ALT levels in tx-J mice Part 3
Completed74
18586Jin Shengkan
Metabolic measurements in B6 mice fed high fat diet and treated with fruit extracts
Completed90
22299Holly Ingraham
Circulating ALT and FFA levels in liver specific Nr5a2 KO mice Part 2
Completed24
22232Holly Ingraham
Circulating ALT levels in liver specific Nr5a2 KO mice treated with AAV8-Lrh1
Completed24
22167Holly Ingraham
Circulating ALT and FFA levels in liver specific Esr1 KO mice
Completed58
22338Jin Shengkan
Circulating insulin, lipid, ALT, and AST levels in B6 mice fed high fat diet and treated with niclosamide
Completed126



Associated MP Terms
  • MP:0001573 - abnormal circulating alanine transaminase level
  • MP:0002941 - increased circulating alanine transaminase level
  • MP:0002942 - decreased circulating alanine transaminase level

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