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Experiment

Circulating cytokine levels in B6 mice treated with NEN, metformin, and
cholestyramine
Summary Data Summary
Investigator Shengkan, Jin
Description C57 mice are fed diet supplemented with 2000ppm niclosamide ethanolamine and/or
supplemented with 20000ppm cholesttyramine in addition to being treated with
metformin in the drinking water.

Applicable research area(s): Diabetes, Endocrine deficiency, Metabolism
Status Completed
Public Release 2/2/2019
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainAnimal CountExperiment Description
Data Analysis
TypeCount
Animals39
Experimental Conditions8
Catalog Items4
Curation Info (# flags)3
Phenotype Assays9
Phenotype Measurements351
Histology Images0
Publications0
Phenotypes2


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6J
0
39
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Administered

 Metformin
Metformin is a drug approved by the U.S. Food and Drug Administration as a prescription medication to treat diabetes. This medication is used to decrease hepatic (liver) glucose production, to decrease GI glucose absorption and to increase target...
 No Drug/Treatment
No Drug or Treatment done on these samples

Experimental Factor: Drug Dose Units

 mg/kg/d
milligrams per kilograms per day

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Feeding Group

 Fasted
Animals are deprived of food but not water.

Experimental Factor: Mouse Diet

 Research Diets - D09032705G
Rodent diet 40% kcal fat, 43% kcal carbohydrate, 17% kcal protein
 Research Diets - D16012604
Rodent diet 40% kcal fat, 43% kcal carbohydrate, 17% kcal protein supplemented with 2000 ppm niclosamide ethanolamine (NEN)
 Research Diets - D16012605
Rodent diet 40% kcal fat, 43% kcal carbohydrate, 17% kcal protein supplemented with 2000 ppm niclosamide ethanolamine (NEN) and 2% cholestyramine (COL)

Experimental Factor: Tissue Source

 serum
serum
Experimental Factor Values


No documents found.

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