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Phenotype Assay
aspartate aminotransferase (AST)
units per liter (U/L)

Name aspartate aminotransferase
Abbreviation AST
Is Categorical? False
Tissue(s) liver
Group(s) enzymes
Description Aspartate transaminase (AST) catalyzes the reversible transfer of an a-amino
group between aspartate and glutamate and, as such, is an important enzyme in
amino acid metabolism. AST is found in the liver, heart, skeletal muscle,
kidneys, brain, and red bl
Protocol Not Specified

Experiments
OrderInvestigatorExperimentStatusMeasurements
3045030450Claudia Rodrigues
Circulating ALT, AST levels in Myc KO mice fed high fat and high cholesterol diet
Completed74
3040730407Claudia Rodrigues
Circulating lipid levels and ALT, AST levels in Myc KO mice fed high fat and high cholesterol diet
Completed185
2176521765Pei-Yu Chen
4M WT atherosclerosis
Completed70
3035830358Jin Shengkan
Circulating ALT, and AST levels in B6 mice treated with derivatives of niclosamide and CCL4
Completed104
3041230412Jin Shengkan
Circulating lipid, insulin, ALT and AST levels in Lepr KO mice treated with derivatives of niclosamide
Completed384
2073520735Pei-Yu Chen
TGFb signaling in atherosclerosis.
Completed200
2561225612Jin Shengkan
Circulating albumin, ALT, and AST levels in B6 mice treated with niclosamide and CCL4
Completed120
2556225562Jin Shengkan
Circulating insulin, lipid, ALT, and AST levels in B6 mice treated with niclosamide
Completed33
2235022350Holly Ingraham
Circulating FFA, AST, and insulin levels in liver specific Esr1 KO mice
Completed42
2073220732Noemi Rotllan Vila
Influence of the treatment with miR-148a LNA on hepatic lipid metabolism
Completed96
2233822338Jin Shengkan
Circulating insulin, lipid, ALT, and AST levels in B6 mice fed high fat diet and treated with niclosamide
Completed126
1858618586Jin Shengkan
Metabolic measurements in B6 mice fed high fat diet and treated with fruit extracts
Completed90
2210822108Jin Shengkan
Circulating cytokine levels in B6 mice treated with NEN, metformin, and cholestyramine
Completed351
2183221832Jin Shengkan
Metabolic measurements in ApoE KO mice treated with metformin and niclosamide pt2
Completed360
2181321813Jin Shengkan
Metabolic measurements in ApoE KO mice treated with metformin and niclosamide
Completed225
2072420724Jin Shengkan
Metabolic measurements in Lipa KO mice treated with niclosamide
Completed98
24922492Pei-Yu Chen
Cobas Order # 2492
Completed36
1858318583Anand Narayanan
Pathophysiology of metabolism and atherosclerosis 2
Completed72
1851318513Anand Narayanan
lipid profile in blood in TCF7l2 of over-expression
Completed55
1846818468Anand Narayanan
Pathophysiology of metabolism and atherosclerosis
Completed78
1100311003Valentina Medici
Circulating ALT and AST levels in tx-J KO mice
Completed173
18151815Laurie Minze
Experiment for Order #1815
Completed54
18101810Laurie Minze
Experiment for Order #1810
Completed186
16211621Romina Fiorotto
Notch2 is required for proper IHBD development and morphogenesis.
Completed111
15831583Kristine Pelton
mice with hypercholesterolemia lose cortical and trabecular bone in the femurs and vertebrae
Completed213
2175421754Jessica Costa
Liver-specific loss of Hrpt2
Completed234
1846018460Leigh Goedeke
Influence of miR-148a on hepatic lipid metabolism
Completed79
1963319633Anand Narayanan
Determine lipid profiles in blood in TCF7l2 overexpression mice on chow diet (8 months)
Completed66
1853118531Yen Hao Chen
mice liver and kidney function
Completed45
1332613326Tomas Majtan
Effect of PEG-CBS ERT on liver function of the I278T homocystinuria mouse model
Completed40
25082508Pei-Yu Chen
Cobas Order # 2508
Completed40
22392239Pei-Yu Chen
Cobas 6/8/11 - 2239
Completed0
22532253Huricha Baigude
Cobas 6/15/11
Completed0
21732173Lianfu Wang
4/25/11
In Progress0
17601760Miguel Ortiz
Experiment for Order #1760
In Progress136



Associated MP Terms
  • MP:0000203 - abnormal circulating aspartate transaminase level
  • MP:0005343 - increased circulating aspartate transaminase level
  • MP:0005632 - decreased circulating aspartate transaminase level

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