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Experiment

Effect of PEG-CBS ERT on liver function of the I278T homocystinuria mouse model
Summary Data Summary
Investigator Majtan, Tomas
Description Transgenic I278T mice, one of the mouse models for cystathionine beta-synthase
(CBS)-deficient homocystinuria, were treated with an experimental enzyme
replacement therapy (ERT) for homocystinuria, designated as PEG-CBS, and
compared to untreated affected homozygous and untreated healthy heterozygous
mice.
Status Completed
Public Release 2/4/2018
Animal Age Measured In: month(s) post-natal (m)
Flags has-data-flagSame Strain
Data Analysis
TypeCount
Animals10
Experimental Conditions1
Catalog Items4
Curation Info (# flags)1
Phenotype Assays4
Phenotype Measurements40
Histology Images0
Publications0
Phenotypes2


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6
0
4
0
Tg-I278T
2
4
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.
Experimental Factor (Units)
Experimental Group
Experimental Factor Values


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