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Experiment

Influence of Myo K64A mutation on glucose tolerance and insulin stimulate AKT
signaling
Summary Data Summary
Investigator Adams, Sean
Description 26 mice (male w/littermate control, 14 WT and 12 Hom). Animals will be placed on
high-fat (HFD) diet at ~6 weeks of age and GTT will be completed at 10 weeks on
diet (age=~15 w). Mice will be terminated after an IP injection of saline or
insulin at 11 weeks on diet (age ~16 weeks), and plasma/tissues collected at 18
weeks of age.

Applicable research areas: Diabetes, Metabolism, Obesity
Status Completed
Public Release 1/7/2022
Animal Age Measured In: week(s) post-natal (w)
Data Analysis
TypeCount
Animals26
Experimental Conditions5
Catalog Items1
Curation Info (# flags)0
Phenotype Assays1
Phenotype Measurements130
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6N +/+
0
14
0
MbKA
0
12
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Delivery Route

 IP
The drug was delivered intraperitoneal.

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 Teklad - 08511
45% Fat Kcal Diet (ISP) -- The mid-fat diet in a series of diets with isolated soy protein, 10, 45, or 60% kcal from fat, with ~43% of the total carbohydrate from sucrose, and equivalent vitamin and mineral levels adjusted on an energy basis....
Experimental Factor Values


Phenotype Assays Add / Edit


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