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Experiment

Lipoprotein profiles of Nrf1LKO on Western Diet (D12109) / MGSHHSOPH1014(2)
Summary Data Summary
Investigator Hotamisligil, Gokhan
Description This model is valuable for understanding protective mechanisms to liver
cholesterol accumulation.

These mice accumulate cholesterol in their livers.

Applicable research area(s): Cardiovascular
Status Completed
Public Release 2/23/2017
Animal Age Measured In: week(s) post-natal (w)
Data Analysis
TypeCount
Animals14
Experimental Conditions2
Catalog Items3
Curation Info (# flags)0
Phenotype Assays8
Phenotype Measurements112
Histology Images0
Publications0
Phenotypes1


Animals

Strain NameCommon NameFemalesMalesUnknown
B6.Cg-Tg(Alb-cre)21Mgn/J
0
7
0
C57BL/6J-Tg(Alb-cre)21Mgn Nrf1lox/lox
0
7
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 Research Diets - D12109C
Atherogenic Rodent Diet With 1.25% Cholesterol, 0.5% Cholic Acid, and 17% (w/w) Cocoa Butter.
 Teklad - 7912
Irradiated 7012 Teklad LM-485 Mouse/Rat Sterilizable Diet. Crude Protein 19.1%, Fat (ether extract) 5.8%, Crude Fiber 4.6%, Energy Density 3.1 kcal/g, Calories from Protein 25%, Calories from Fat 17%, Calories from Carbohydrate 58%. A fixed...
Experimental Factor (Units)
Experimental Group
Mouse Diet



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