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Experiment

Hyperinsulinemic euglycemic clamp and Sable energy balance order #13236
Summary Data Summary
Investigator Lin, Dingbo
Description BCO2/129S6 develops more obese phenotype compared with the genetic background
129S6 when fed a high fat diet. Those mice show altered mitochondrial
activities.

Applicable research area(s): Diabetes, Obesity, Endocrine deficiency, Metabolism
Status Completed
Public Release 3/11/2017
Animal Age Measured In: week(s) post-natal (w)
Data Analysis
TypeCount
Animals16
Experimental Conditions5
Catalog Items3
Curation Info (# flags)0
Phenotype Assays26
Phenotype Measurements3994
Histology Images0
Publications0
Phenotypes3


Animals
Strain NameCommon NameFemalesMalesUnknown
129S6/SvEvTac
0
8
0
129S6/SvEvTac-Bco2-/-
0
8
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Glucose Infusion Rate (mg/kg/min)

 Glucose Infusion Rat
Rate of glucose infusion for clamp experiments

Experimental Factor: Insulin Infusion Rate - milliUnits (mU/kg/min)

 Insulin Infusion Rat
This is insulin infusion rate for hyperinsulinemic clamp data

Experimental Factor: Mouse Diet

 Teklad - 7012
Crude Protein (Min) 19.0%, Crude Fat (Min) 5.0%, Crude Fiber (Max) 5.0%, Protein %19.92, Fat %5.67, Fiber %4.37, Ash %6.48, Ingredients - Ground corn, dehulled soybean meal, ground oats, wheat middlings, dehydrated alfalfa meal, soybean oil, corn...

Experimental Factor: Time Sample Taken (min)

 Time Sample Taken
Time in minutes since a sample was taken


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