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Strain
BKS(D)-Leprdb/JOrlRj

Summary Data Summary
Official Name BKS(D)-Leprdb/JOrlRj
Common Name C57BLKS/J db/db
Description A G-to-T transversion in this allele created a donor splice
site that causes abnormal splicing and a 106 nt insertion in
the transcript, leading to premature termination of the long
cellular domain of the Ob-Rb splice form and loss of its
signal transducing function.
Development Status Phenotyping ongoing
Creation Method spontaneous
Background C57BLKS
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 1


Investigators
NameInstitution
Pascal SirventBlaise Pascal University


Genomic Information
GeneAllele 1Allele 2Protocol
Leprpoint mutation - transitionpoint mutation - transitionNot Specified


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