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Strain
C57BL/6J-Sptlc2tm1Cha Tg(Adipoq-Cre)

Summary Data Summary
Official Name C57BL/6J-Sptlc2tm1Cha Tg(Adipoq-Cre)
Common Name C57BL/6J-Sptlc2lox/lox Tg(Adipoq-Cre)
Description This strain contains a conditional knockout of the Sptlc2
gene. Mice homozygous for a knock-out allele exhibit
embryonic lethality. Mice heterozygous for the knockout
exhibit abnormal liver and circulating shingolipid levels.
The Cre gene is driven by the Adipoq promoter.
Development Status Phenotyping ongoing
Creation Method knockout
Background C57BL/6J
TypeCount
Investigators 1
Genomics - Modifications 1
Genomics - Transgenes 1
Experiments 1


Investigators
NameInstitution
Bhagirath ChaurasiaUniversity of Utah


Genomic Information
GeneAllele 1Allele 2Protocol
Sptlc2knockin (lox)knockin (lox)Not Specified
EnhancerPromoterGeneCopies
Not SpecifiedAdipoqCRENot Specified


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