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Strain
B6;FVB-Srebf2tm1Jdh Tg(Gfap-Cre)8Gtm Tg(Gfap-GFP)14Mes

Summary Data Summary
Official Name B6;FVB-Srebf2tm1Jdh Tg(Gfap-Cre)8Gtm Tg(Gfap-GFP)14Mes
Common Name B6;B6.Cg;FVB/N-Srebf2tm1Jdh Tg(Gfap-cre)8Gtm/Nci Tg(Gfap-GFP)14Mes/J
Description The Srebf2 gene was floxed by Jay D. Horton, with the glial
fibrillary acidic protein (Gfap) gene promoter driving the
Cre gene by crossing the floxed strain to
B6.Cg-Tg(Gfap-cre)8Gtm/Nci. In addition, Green Fluorescent
protein (GFP) was also introduced by crossing to
FVB/N-Tg(GFAPGFP)14Mes/J.

Srebf2 flox: The targeting vector contains a loxP site
inserted into the promoter region 660 bp upstream of exon 1
and a loxP site followed by a FRT-flanked neomycin cassette
inserted into intron 1.
Development Status Phenotyping ongoing
Creation Method knockin
TypeCount
Investigators 1
Genomics - Modifications 1
Genomics - Transgenes 2
Experiments 1


Investigators
NameInstitution
C. Ronald KahnJoslin Diabetes Center - Boston


Genomic Information
GeneAllele 1Allele 2Protocol
Srebf2knockin (lox)knockin (lox)Not Specified
EnhancerPromoterGeneCopies
Not SpecifiedGfapCRENot Specified
Not SpecifiedGfapGFPNot Specified


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