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Strain
C56BL/6-Tg(Prnp-Manf)1Yang

Summary Data Summary
Official Name C56BL/6-Tg(Prnp-Manf)1Yang
Common Name C56BL/6-Tg(Prnp-Manf)1Yang
Description Contains transgene where the mouse prion promoter (Prnp) is
driving the mouse mesencephalic astrocyte-derived
neurotrophic factor (Manf) gene.
Development Status Phenotyping ongoing
Creation Method transgenic
Breeding Type intercross
Phenotype Description MANF transgenic mice became significantly obese at the age
of 4-month old. They also exhibited hyperphagia activity. At
the age of 2-month, they had a significantly higher level of
blood glucose and insulin.
TypeCount
Investigators 1
Genomics - Transgenes 1
Experiments 1


Investigators
NameInstitution
Su YangEmory University


Genomic Information
EnhancerPromoterGeneCopies
Not SpecifiedPrnpManfNot Specified


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