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Sable Energy Balance #19660 2/29/16
Summary Data Summary
Investigator Yang, Su
Description Energy expenditure measured by indirect calorimetry in the Promethion by Sable
Systems. Activity, food intake and water intake are also continuously measured.
Measurements were taken for 5 consecutive days.
Running wheels were not present in the cage.
Mice were fed ad libitum.
Water: regular tap water, ad libitum.

Male and Female WT(C57BL/6) and TG (C56BL/6-Tg(Prnp-Manf)1Yang) mice.
Mice were fed a chow diet (HarlanTD7012).
Male WT Chow: n=4
Male TG Chow: n=4
Female WT Chow: n=4
Female TG Chow: n=4

Purpose of the experiment: This experiment will determine whether the groups of
mice have different energy expenditure and feeding behaviors.

Applicable Research Areas: Metabolism , Body weight regulation, energy
expenditure, feeding behavior.
Status Completed
Public Release 5/3/2018
Animal Age Measured In: day(s) post-natal (d)
Data Analysis
Experimental Conditions2
Catalog Items1
Curation Info (# flags)0
Phenotype Assays14
Phenotype Measurements224
Histology Images0

Strain NameCommon NameFemalesMalesUnknown

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

This animal belongs to the control group for the experiment.
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 Teklad - 7012
Crude Protein (Min) 19.0%, Crude Fat (Min) 5.0%, Crude Fiber (Max) 5.0%, Protein %19.92, Fat %5.67, Fiber %4.37, Ash %6.48, Ingredients - Ground corn, dehulled soybean meal, ground oats, wheat middlings, dehydrated alfalfa meal, soybean oil, corn...
Experimental Factor (Units)
Experimental Group
Mouse Diet

No documents found.

Mammalian Phenotype (MP) Terms
MPTermIDMPTermNameDefinitionOther Results
MP:0000679increased percent water in carcass
more than the normal total amount of water retained in the body measured post mortem [MGI:il]
MMPC Search Results
MP:0001260increased body weight
greater than normal average weight [J:33400]
MMPC Search Results
MP:0003960increased lean body mass
greater amount of the fat-free physical bulk or volume of the body including all its components except adipose (fat) tissue [MGI:csmith]
MMPC Search Results
MP:0005289increased oxygen consumption
greater than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body [MESH:G06.535.723]
MMPC Search Results
MP:0008963increased carbon dioxide production
increase in the rate at which carbon dioxide leaves the blood and enters the alveolar gas [MGI:csmith]
MMPC Search Results
MP:0010024increased total body fat amount
greater than the normal total amount of connective tissue composed of fat cells within the entire body [MGI:csmith]
MMPC Search Results
MP:0011940decreased food intake
reduction in the total number of calories or food amount taken in over time when compared to the normal state [MGI:csmith]
MMPC Search Results
MP:0011946decreased eating frequency
reduction in the number of discrete instances of initiation of eating over time| regardless of amount eaten [MGI:csmith]
MMPC Search Results
MP:0014142increased body fat mass
increased physical bulk or volume of fat in the whole body [MGI:csmith]
MMPC Search Results


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