| Create Account | login

login

Experiment

Sable Energy Balance #19660 2/29/16

Summary

Data Summary

Investigator	Yang, Su
Description	Energy expenditure measured by indirect calorimetry in the Promethion by Sable Systems. Activity, food intake and water intake are also continuously measured. Measurements were taken for 5 consecutive days. Running wheels were not present in the cage. Mice were fed ad libitum. Water: regular tap water, ad libitum. Groups: Male and Female WT(C57BL/6) and TG (C56BL/6-Tg(Prnp-Manf)1Yang) mice. Mice were fed a chow diet (HarlanTD7012). Male WT Chow: n=4 Male TG Chow: n=4 Female WT Chow: n=4 Female TG Chow: n=4 Purpose of the experiment: This experiment will determine whether the groups of mice have different energy expenditure and feeding behaviors. Applicable Research Areas: Metabolism , Body weight regulation, energy expenditure, feeding behavior.
Status	Completed
Public Release	5/3/2018
Animal Age	Measured In: day(s) post-natal (d)
Flags

Data Analysis

DOWNLOAD ALL DATA (.csv)

Type	Count
Animals	16
Experimental Conditions	2
Catalog Items	1
Curation Info (# flags)	0
Phenotype Assays	14
Phenotype Measurements	224
Histology Images	0
Publications	0
Phenotypes	9

Animals

Strain Name	Common Name	Females	Males	Unknown
C57BL/6	C57BL/6	4	4	0
C56BL/6-Tg(Prnp-Manf)1Yang	C56BL/6-Tg(Prnp-Manf)1Yang	4	4	0

Animals/Strains

Experimental Factors

	Categorical Values
	Name / Abbreviation	Description
	Experimental Factor: Experimental Group
	Control	This animal belongs to the control group for the experiment.
	Experiment	This animal belongs to experimental group that is homozygous for gene manipulations.
	Experimental Factor: Mouse Diet
	Teklad - 7012	Crude Protein (Min) 19.0%, Crude Fat (Min) 5.0%, Crude Fiber (Max) 5.0%, Protein %19.92, Fat %5.67, Fiber %4.37, Ash %6.48, Ingredients - Ground corn, dehulled soybean meal, ground oats, wheat middlings, dehydrated alfalfa meal, soybean oil, corn...

Experimental Factor (Units)
Experimental Group
Mouse Diet

Experimental Factor Values

Phenotype Assays Add / Edit

Name	Abbreviation
body mass	W rodent
oxygen consumption (Light Period)	VO2-L
fat body mass	fat body mass
lean body mass	lean body mass
respiratory exchange ratio (Light Period)	RER-L
body water, free	free water
heat (Light Period)	HEAT-Light
oxygen consumption (Dark Period)	VO2-D
carbon dioxide production Light Period	VCO2-L
carbon dioxide production Dark Period	VCO2-D
respiratory exchange ratio (Dark Period)	RER-D
heat (Dark Period)	HEAT-Dark
temperature, environmental	ENV TEMP
food intake	food intake

No documents found.

Mammalian Phenotype (MP) Terms

MPTermID	MPTermName	Definition	Other Results
MP:0000679	increased percent water in carcass	more than the normal total amount of water retained in the body measured post mortem [MGI:il]	MMPC Search Results
MP:0001260	increased body weight	greater than normal average weight [J:33400]	MMPC Search Results
MP:0003960	increased lean body mass	greater amount of the fat-free physical bulk or volume of the body including all its components except adipose (fat) tissue [MGI:csmith]	MMPC Search Results
MP:0005289	increased oxygen consumption	greater than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body [MESH:G06.535.723]	MMPC Search Results
MP:0008963	increased carbon dioxide production	increase in the rate at which carbon dioxide leaves the blood and enters the alveolar gas [MGI:csmith]	MMPC Search Results
MP:0010024	increased total body fat amount	greater than the normal total amount of connective tissue composed of fat cells within the entire body [MGI:csmith]	MMPC Search Results
MP:0011940	decreased food intake	reduction in the total number of calories or food amount taken in over time when compared to the normal state [MGI:csmith]	MMPC Search Results
MP:0011946	decreased eating frequency	reduction in the number of discrete instances of initiation of eating over time\| regardless of amount eaten [MGI:csmith]	MMPC Search Results
MP:0014142	increased body fat mass	increased physical bulk or volume of fat in the whole body [MGI:csmith]	MMPC Search Results

Back to Top

Store Credentials?

MMPC-Live web resource – Terms of Use

Warranty disclaimer and copyright notice

THE MMPC-Live MAKES NO REPRESENTATION ABOUT THE SUITABILITY OR ACCURACY OF THE SOFTWARE OR DATA FOR ANY PURPOSE, AND MAKES NO WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR THAT THE USE OF THE SOFTWARE OR DATA WILL NOT INFRINGE ANY THIRD PARTY PATENTS, COPYRIGHTS, TRADEMARKS, OR OTHER RIGHTS. THE SOFTWARE AND DATA ARE PROVIDED "AS IS".

The Mouse Metabolic Phenotyping Centers (MMPC-Live) is an NIDDK funded consortium and adheres to the NIH Data Sharing Policy.

MMPC-Live clients make their data freely available whereby MMPC-Live users may freely build upon, enhance and reuse those data for any purpose without restriction. Scholarly citation norms must be followed for content reuse. Please acknowledge the MMPC-Live using the following text: 'The MMPC-Live data used in this manuscript was supported by the NIDDK National Mouse Metabolic Phenotyping Centers (MMPC-Live, RRID:SCR_008997, www.mmpc.org)'. To cite specific MMPC-Live centers, please use the appropriate RRID available from the MMPC-Live website (https://www.mmpc.org/shared/centers.aspx).

Please note that the acknowledgment text includes a Research Resource Identifier (RRID) for the MMPC-Live CU and Centers. Reproducibility is one of the corner stones of effective, open and transparent biomedical published research. However, too often, resources (e.g. model organisms, antibodies, and tools) are not reported with adequate detail to ensure others can replicate or expand upon the published results. The Research Resource Identification Initiative (#RII) seeks to change these limitations in reporting by the use of unique Research Resource Identifiers (RRIDs). This initiative is designed to encourage authors to provide identification of the types of resources used in their research by adding a globally unique accession number to the resources described in the their manuscripts. These identifiers, called RRIDs, will allow authors to cite the resources that they use in their manuscripts. RRIDs allow for easy tracking of all papers that have used the same resource making it easy to access how the same resources works in other scenarios.

It is expected that MMPC-Live users follow scholarly citation norms, giving credit to fellow scholars when accessing/using protocols and data, including data derived by MMPC-Live (such as summary data) and any plots, tables or screenshots depicting those data.

It is possible for invalid or incomplete results to be presented on the MMPC-Live web site due to software bugs, data problems, or artifacts of human error. Data sets are not necessarily static; we reserve the right to post corrections and updates as needed.

Prohibited use. Data contributors and data users may not use MMPC-Live in any unlawful manner, or in any manner that could impair MMPC-Live services, security or functionality. Automated usage (webcrawlers and similar) must observe each page's "meta robots" html tags and space requests by ≥ 2 seconds. We reserve the right to block any IP associated with what we consider to be excessive or abusive usage patterns, and/or to take any action we deem necessary.

MMPC-Live is a National Institutes of Health-sponsored resource that provides experimental testing services to scientists studying diabetes, obesity, diabetic complications, and other metabolic diseases in mice.

Menu

Home

Contact

About MMPC

Animal Husbandry

Tests Data

Search Data

Analysis

Clients

MMPC Centers

Newsletter

Interested in receiving MMPC News?

Mouse Phenotyping
@NationalMMPC

2017 National MMPC. All Rights Reserved.