mmpc-logo mmpc-logo
twitter-logo    bluesky-logo
| Create Account | login
Strain
B6J.Cg-Mapk9tm2.1Rjd Mapk8tm1Rjd Lyz2tm1(cre)Ifo

Summary Data Summary
Official Name B6J.Cg-Mapk9tm2.1Rjd Mapk8tm1Rjd Lyz2tm1(cre)Ifo
Common Name Macrophage specific JNK1/2 DKO
Development Status Phenotyping ongoing
Creation Method transgenic
TypeCount
Investigators 1
Genomics - Modifications 3
Genomics - Transgenes 1
Experiments 1
Publications 2


Investigators
NameInstitution
Roger J. DavisUniversity of Massachusetts Medical School


Genomic Information
GeneAllele 1Allele 2Protocol
Mapk8knockin (lox)knockin (lox)Not Specified
Mapk9knockin (lox)knockin (lox)Not Specified
Lyz2knockin (Cre)knockin (Cre)Not Specified
EnhancerPromoterGeneCopies
Not SpecifiedLyz2CRENot Specified






PublicationAltmetricsSubmitted ByPubMed IDStatus
JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation.
Han MS, Jung DY, Morel C, Lakhani SA, Kim JK, Flavell RA, Davis RJ
Science (New York, N.Y.), 2013 (339), 218 - 222
23223452
Published
Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes.
Perry RJ, Camporez JP, Kursawe R, Titchenell PM, Zhang D, Perry CJ, Jurczak MJ, Abudukadier A, Han MS, Zhang XM, Ruan HB, Yang X, Caprio S, Kaech SM, Sul HS, Birnbaum MJ, Davis RJ, Cline GW, Petersen KF, Shulman GI
Cell, 2015 (160), 745 - 58
Submitted Externally
25662011
Published

Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.