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Strain
C57BL/6-Xbp1tm1Glm

Summary Data Summary
Official Name C57BL/6-Xbp1tm1Glm
Common Name Xbp1 KO
Description A 0.8 kb genomic region between exons 1 and 2 was replaced
with a neomycin resistance cassette via homologous
recombination resulting in a shift in the downstream reading
frame. Northern blot analysis of homozygous mutant embryos
did not detect wild-type transcript, but instead detected a
larger mutant transcript which contained the neo insert.
Western blot of fetal livers did not detect protein product
in homozygous mutants.
Development Status Phenotyping ongoing
Creation Method knockout
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 5


Investigators
NameInstitution
Muhammad Abdul-GhaniAcademy for Practical Nursing & Health Occupations


Genomic Information
GeneAllele 1Allele 2Protocol
Xbp1knockoutknockoutNot Specified


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