mmpc-logo
twitter-logo @NationalMMPC
| Create Account | login
Strain
C57BL/6-Xbp1tm1Glm

Summary Data Summary
Official Name C57BL/6-Xbp1tm1Glm
Common Name Xbp1 KO
Description A 0.8 kb genomic region between exons 1 and 2 was replaced
with a neomycin resistance cassette via homologous
recombination resulting in a shift in the downstream reading
frame. Northern blot analysis of homozygous mutant embryos
did not detect wild-type transcript, but instead detected a
larger mutant transcript which contained the neo insert.
Western blot of fetal livers did not detect protein product
in homozygous mutants.
Development Status Phenotyping ongoing
Creation Method knockout
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 1


Investigators
NameInstitution
Muhammad Abdul-GhaniAcademy for Practical Nursing & Health Occupations


Genomic Information
GeneAllele 1Allele 2Protocol
Xbp1knockoutknockoutNot Specified


Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.