mmpc-logo mmpc-logo
twitter-logo    bluesky-logo
| Create Account | login
Strain
C57BL/6N-Mecp2tm1.1Dhy -/+

Summary Data Summary
Official Name C57BL/6N-Mecp2tm1.1Dhy -/+
Common Name C57BL/6N-Mecp2tm1.1Dhy -/+
Description Exon 1 was replaced with a modified exon 1 in which a
nucleotide substitution of A to T results in the destruction
of the translation initiation site. Flp-mediated
recombination removed the FRT-flanked neomycin resistance
cassette inserted downstream of the modified exon 1. Western
blot analysis confirmed the absence of e1 isoform expression
and preserved e2 isoform expression in the brain.

Mutation is X-linked.
Development Status Phenotyping ongoing
Creation Method knockin
Breeding Type intercross
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 1


Investigators
NameInstitution
Dag YasuiUniversity of California Davis


Genomic Information
GeneAllele 1Allele 2Protocol
Mecp2knockinwildNot Specified


Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.