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Strain
B6.129-Traf3ip2tm1Sbn

Summary Data Summary
Official Name B6.129-Traf3ip2tm1Sbn
Common Name B6.129-Traf3ip2tm1Sbn
Description A 3.6 Kb BamHI fragment containing exon 2 was replaced with
a neomycin selection cassette. Correct targeting was
confirmed by Southern blotting. Analysis of mRNAs from
homozygote B cells demonstrates exon 1 was spliced to exon
3. All potential ATG start codons upstream of exon 3 and
located in the correct reading frame are followed by at
least 2 stop codons prior to the start of exon 3. The first
ATG present within the functional reading frame downstream
of the start of exon 3 is located in exon 5, which could
only generate a 157 amino acid long fragment of the 555
amino acid endogenous protein. For these reasons, a
functional protein product was considered unlikely.
Development Status Not specified/Other
Creation Method chemical induced
TypeCount
Genomics - Modifications 1
Experiments 1


Genomic Information
GeneAllele 1Allele 2Protocol
Traf3ip2knockoutknockoutNot Specified


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