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Strain
C57BL/6-Ralgapbtm1a(KOMP)Wtsi

Summary Data Summary
Official Name C57BL/6-Ralgapbtm1a(KOMP)Wtsi
Common Name C57BL/6-Ralgapbtm1a(KOMP)Wtsi
Description The L1L2_Bact_P cassette was inserted at position 158271857
of Chromosome 2 upstream of the critical exon(s) (Build
GRCm39). The cassette is composed of an FRT site followed by
lacZ sequence and a loxP site. This first loxP site is
followed by a neomycin resistance gene under the control of
the human beta-actin promoter, SV40 polyA, a second FRT site
and a second loxP site. A third loxP site is inserted
downstream of the targeted exon(s) at position 158272768.
The critical exon(s) is/are thus flanked by loxP sites. A
"conditional ready" (floxed) allele can be created by flp
recombinase expression in mice carrying this allele.
Subsequent cre expression results in a knockout mouse. If
cre expression occurs without flp expression, a reporter
knockout mouse will be created.
Development Status Phenotyping ongoing
Creation Method knockout
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 1


Investigators
NameInstitution
Shuai ChenUniversity in Nanjing, China · Gulou Qu


Genomic Information
GeneAllele 1Allele 2Protocol
RalgapbknockoutknockoutNot Specified


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