mmpc-logo mmpc-logo
twitter-logo @NationalMMPC
| Create Account | login
Strain
C57BL/6-Ralgapbtm1a(KOMP)Wtsi

Summary Data Summary
Official Name C57BL/6-Ralgapbtm1a(KOMP)Wtsi
Common Name C57BL/6-Ralgapbtm1a(KOMP)Wtsi
Description The L1L2_Bact_P cassette was inserted at position 158271857
of Chromosome 2 upstream of the critical exon(s) (Build
GRCm39). The cassette is composed of an FRT site followed by
lacZ sequence and a loxP site. This first loxP site is
followed by a neomycin resistance gene under the control of
the human beta-actin promoter, SV40 polyA, a second FRT site
and a second loxP site. A third loxP site is inserted
downstream of the targeted exon(s) at position 158272768.
The critical exon(s) is/are thus flanked by loxP sites. A
"conditional ready" (floxed) allele can be created by flp
recombinase expression in mice carrying this allele.
Subsequent cre expression results in a knockout mouse. If
cre expression occurs without flp expression, a reporter
knockout mouse will be created.
Development Status Phenotyping ongoing
Creation Method knockout
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 1


Investigators
NameInstitution
Shuai ChenUniversity in Nanjing, China · Gulou Qu


Genomic Information
GeneAllele 1Allele 2Protocol
RalgapbknockoutknockoutNot Specified


Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.