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Strain
C57Bl/6-Chrna2tm1jwu Tg (Adipoq-Cre)1Evdr/J

Summary Data Summary
Official Name C57Bl/6-Chrna2tm1jwu Tg (Adipoq-Cre)1Evdr/J
Common Name C57Bl/6-Chrna2tm1jwu Tg(Adipoq-Cre)1Evdr/J
Description Chrna2 flox/flox knockout made in lab and fully back crossed
>10 generations.
Mice harboring the Adipoq-Cre BAC transgene express Cre
recombinase under control of the mouse adiponectin (Adipoq)
promoter/enhancer regions within the BAC transgene.
Adipoq-Cre BAC transgenic mice are a Cre-lox tool for
deletion of floxed sequences in white adipose tissue and
brown adipose tissue, but not in activated or resident
macrophages.
Development Status Phenotyping ongoing
Creation Method knockout
Breeding Type backcross
TypeCount
Investigators 1
Genomics - Modifications 1
Genomics - Transgenes 1
Experiments 4


Investigators
NameInstitution
Jun WuUniversity of Michigan-Ann Arbor


Genomic Information
GeneAllele 1Allele 2Protocol
Chrna2knockoutknockoutNot Specified
EnhancerPromoterGeneCopies
Not SpecifiedAdipoqCRENot Specified


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