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Strain
C57BL/6J-Lepob

Summary Data Summary
Official Name C57BL/6J-Lepob
Common Name C57BL/6J ob/ob
Description Sequencing of RT-PCR products revealed a nonsense mutation
in codon 105 resulting from a C to T point mutation. The 16
kDa leptin protein, expressed predominantly in adipose
tissue of normal mice, is missing from homozygous mutant
mice
Development Status Not specified/Other
Creation Method spontaneous
Maternal Strain C57BL/6J
Paternal Strain C57BL/6J
Background C57BL/6J
Breeding Type intercross
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 2


Investigators
NameInstitution
Anton WellsteinGeorgetown University


Genomic Information
GeneAllele 1Allele 2Protocol
Leppoint mutation - transitionpoint mutation - transitionNot Specified


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