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Experiment

Sable Energy Balance #22085 10/21/16
Summary Data Summary
Investigator Stafford, John
Description Energy expenditure measured by indirect calorimetry in the Promethion by Sable
Systems. Activity, food intake and water intake are also continuously measured.
Measurements were taken for 4 consecutive days.
Running wheels were not present in the cage.
Mice were fed ad libitum.
Water: regular tap water, ad libitum.

Groups:
Male and Female WT (C57BL/6J) and Cre+ (C57BL/6J-Tg(Alb-cre)21Mgn Nr0b2tm1Lee
[C57BL/6J-Tg(Alb-cre)21Mgn Nr0b2lox/lox]) mice.
Mice were fed a high fat diet (Research Diets - D12492).
Male WT HF: n=7
Male Cre+ HF: n=5
Female WT HF: n=5
Female Cre+ HF: n=7

Purpose of the experiment: This experiment will determine whether the groups of
mice have different energy expenditure and feeding behaviors.

Applicable Research Areas: Metabolism , Body weight regulation, energy
expenditure, feeding behavior.
Status Completed
Public Release 12/7/2018
Animal Age Measured In: day(s) post-natal (d)
Data Analysis
TypeCount
Animals24
Experimental Conditions2
Catalog Items1
Curation Info (# flags)0
Phenotype Assays14
Phenotype Measurements336
Histology Images0
Publications0


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6J
5
7
0
C57BL/6-Nr0b2lox/lox Tg(Alb-cre)21Mgn
7
5
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 Research Diets - D12492
Rodent Diet with 34% Fat, 60% kcal from Fat



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