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Experiment

Sable Energy Balance #22123 12/19/16
Summary Data Summary
Investigator Simerly, Richard
Description Energy expenditure measured by indirect calorimetry in the Promethion by Sable
Systems. Activity, food intake and water intake are also continuously measured.
Measurements were taken for 5 consecutive days. Running wheels were not present
in the cage. Mice were fed ad libitum. Water: regular tap water, ad libitum.

Groups:
Male WT C57BL/6J and KO C57BL/6J-Mc4rtm1Dhu mice.
Mice were fed a chow diet (LabDiet PicoLab Rodent Diet 5LOD).
Male WT Chow: n=7
Male KO Chow: n=7

Purpose of the experiment: This experiment will determine whether the groups of
mice have different energy expenditure and feeding behaviors.

Applicable Research Areas: Metabolism , Body weight regulation, energy
expenditure, feeding behavior.
Status Completed
Public Release 2/8/2019
Animal Age Measured In: day(s) post-natal (d)
Flags has-data-flag
Data Analysis
TypeCount
Animals14
Experimental Conditions3
Catalog Items1
Curation Info (# flags)0
Phenotype Assays14
Phenotype Measurements392
Histology Images0
Publications0
Phenotypes7


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6J
0
7
0
Mc4r-/-
0
7
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 LabDiet PicoLab Rodent Diet 5LOD
Crude Protein 23%, crude fat 4.5%, crude fiber 6.0%. Ingredients: dehulled soybean meal, ground corn, dried beet pulp, fish meal, ground oats, dehydrated alfalfa meal, cane molasses, brewers dried yeast, wheat germ, whey, porcine animal fat...
Experimental Factor Values


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