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Experiment

Sable Energy Balance #22382 7/19/17
Summary Data Summary
Investigator Lark, Daniel
Description Energy expenditure measured by indirect calorimetry in the Promethion by Sable
Systems. Activity, food intake and water intake are also continuously measured.
Measurements were taken for 14 consecutive days.
Running wheels were present in the cage, but blocked so they could not spin,
during the first part of the run. During the second part of the run wheels were
present in the cage.
Mice were fed ad libitum.
Water: regular tap water, ad libitum.

Groups:
Male WT (C57BL/6J) mice.
Mice were fed a chow diet (LabDiet PicoLab Rodent Diet 5LOD) or a 60% kcal High
Fat Diet (F3282 BioServ).
Status Completed
Public Release 10/4/2019
Animal Age Measured In: day(s) post-natal (d)
Flags has-data-flagSame Strain
Data Analysis
TypeCount
Animals16
Experimental Conditions3
Catalog Items1
Curation Info (# flags)1
Phenotype Assays14
Phenotype Measurements448
Histology Images0
Publications0
Phenotypes10


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6J
0
16
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 BioServ F3282
Rodent Hig Fat Diet. Protein 20.%, Fat 35.5%, Fiber 0.0%, Ash 3.2%, Moisture <5.0%, Carbohydrate 36.3%. Ingredients: Lard, Casein, Dextrose, Sucrose, DL-Methionine, Choline Chloride, Vitamin Mix and Mineral Mix
 LabDiet PicoLab Rodent Diet 5LOD
Crude Protein 23%, crude fat 4.5%, crude fiber 6.0%. Ingredients: dehulled soybean meal, ground corn, dried beet pulp, fish meal, ground oats, dehydrated alfalfa meal, cane molasses, brewers dried yeast, wheat germ, whey, porcine animal fat...

Experimental Factor: Sable Run (RNum)

 Sable Run
The run number for the Sable system used to assess energy expenditure.



No documents found.


Mammalian Phenotype (MP) Terms

MPTermIDMPTermNameDefinitionOther Results
MP:0000679increased percent water in carcass
more than the normal total amount of water retained in the body measured post mortem [MGI:il]
MMPC Search Results
MP:0001260increased body weight
greater than normal average weight [J:33400]
MMPC Search Results
MP:0003960increased lean body mass
greater amount of the fat-free physical bulk or volume of the body including all its components except adipose (fat) tissue [MGI:csmith]
MMPC Search Results
MP:0005289increased oxygen consumption
greater than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body [MESH:G06.535.723]
MMPC Search Results
MP:0008963increased carbon dioxide production
increase in the rate at which carbon dioxide leaves the blood and enters the alveolar gas [MGI:csmith]
MMPC Search Results
MP:0010024increased total body fat amount
greater than the normal total amount of connective tissue composed of fat cells within the entire body [MGI:csmith]
MMPC Search Results
MP:0010379decreased respiratory quotient
reduction in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls [MGI:csmith]
MMPC Search Results
MP:0011940decreased food intake
reduction in the total number of calories/food amount taken in over time when compared to the normal state [MGI:csmith]
MMPC Search Results
MP:0011946decreased eating frequency
reduction in the number of discrete instances of initiation of eating over time| regardless of amount eaten [MGI:csmith]
MMPC Search Results
MP:0014142increased body fat mass
increased physical bulk or volume of fat in the whole body [MGI:csmith]
MMPC Search Results

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