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Strain
B6.Cg-Lepob/J

Summary Data Summary
Official Name B6.Cg-Lepob/J
Common Name ob/ob
Description Sequencing of RT-PCR products revealed a nonsense mutation
in codon 105 resulting from a C to T point mutation. The 16
kDa leptin protein, expressed predominantly in adipose
tissue of normal mice, is missing from homozygous mutant
mice (J:29081).
Creation Method spontaneous
TypeCount
Genomics - Modifications 1
Experiments 8


Genomic Information
GeneAllele 1Allele 2Protocol
Leppoint mutation - transitionpoint mutation - transitionNot Specified


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