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Strain

BALB/c

Summary

Data Summary

Official Name	BALB/c
Common Name	BALB/c
Description	BALB/c mice are particularly well known for the production of plasmacytomas following injection with mineral oil forming the basis for the production of monoclonal antibodies. Although not all BALB/c substrains have been examined for plasmacytoma induction, substrains derived from the Andervont (An) lineage (which includes BALB/cByJ) typically are susceptible, while those descended from BALB/cJ are resistant (see: Potter M, 1985). Mammary tumor incidence is normally low but infection with mammary tumor virus by fostering to MMTV+ C3H mice dramatically increases tumor number and age of onset. BALB/c mice develop other cancers later in life including reticular neoplasms, primary lung tumors, and renal tumors. Rare spontaneous myoepitheliomas arising from myoepithelial cells of various exocrine glands have been observed in both BALB/cJ and BALB/cByJ substrains.
Breeding Type	intercross

Type	Count
Experiments	8

OrderID	Order	Investigator	Experiment	Status	Measurements
26216	26216	William Murphy	Circulating corticosterone levels in BALB/c mice fed high fat diet and treated with bone marrow and splenocyte transplants	Completed	12
25904	25904	William Murphy	Circulating corticosterone levels in BALB/C mice fed high fat diet and treated with whole body irradiation and bone marrow cell transplantation	Completed	14
25694	25694	William Murphy	Circulating glucose and corticosterone levels in a BALB/c GVHD model fed high fat diet	Completed	36
25638	25638	William Murphy	Circulating leptin levels in Rag2 KO mice fed high fat diet	Completed	29
25954	25954	William Murphy	Circulating serum amyloid A levels in B6 mice mice fed high fat diet and treated with whole body irradiation and bone marrow cell transplantation	Completed	17
1071	1071	P. Charles Lin	Echocardiography Order #1071 2/12/05	In Progress	50
13311	13311	David Assis	Evaluation of concanavalin A induced hepatitis.	Completed	26
21754	21754	Jessica Costa	Liver-specific loss of Hrpt2	Completed	234

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