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Tracers in Metabolic Research
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This targeted mutation of the myelocytomatosis oncogene
(Myc) gene may be useful in generating conditional mutations
to study B cell activation and proliferation, neural crest
cell development, and mouse embryonic fibroblast
A single loxP site was inserted into intron 1 and a
loxP-flanked neomycin selection cassette was inserted 3' to
exon 3. The neomycin cassette was removed in ES cells by
transient Cre expression prior to the production of chimeric
Genomics - Modifications
Curation Flag Information
New comment to be added:
Liver lipid levels in Myc KO mice fed high fat and high cholesterol diet
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Financial support for this work was provided by the NIDDK Mouse Metabolic Phenotyping Centers (National MMPC, RRID:SCR_008997,
) under the MICROMouse Program, grants DK076169.
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