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Strain
STOCK Lepr-flptm1.1KniGlp1rtm1.1(cre)Lbrl-Gt(ROSA)26Sortm3.2(CAG-EGFP,-CHRM3*/mCherry/Htr2a)Pjen/J

Summary Data Summary
Official Name STOCK Lepr-flptm1.1KniGlp1rtm1.1(cre)Lbrl-Gt(ROSA)26Sortm3.2(CAG-EGFP,-CHRM3*/mCherry/Htr2a)Pjen/J
Common Name STOCK Lepr-flptm1.1KniGlp1rtm1.1(cre)Lbrl-Gt(ROSA)26Sortm3.2(CAG-EGFP,-CHRM3*/mCherry/Htr2a)Pjen/J
Description The LepR-flp was made by Zack Knight and is pending
publication by their lab.
Glp1R-Cre is from Jax (stock no. 029283).
The 3Dq is also from Jax (stock no. 026942).
Glp1r-ires-Cre mice have an IRES-Cre fusion protein inserted
3 base pairs downstream of the stop codon of the
glucagon-like peptide 1 receptor (Glp1r) gene.
RC::FL-hM3Dq is a dual recombinase-responsive Gq-coupled
DREADD allele with a frt-flanked STOP and a cre-dependent
FLEx switch containing an eGFP sequence and an inverted
hM3Dq/mCherry/2ACT88 fusion protein. Flp-recombinase results
in widespread, robust eGFP fluorescence, and further
exposure to Cre recombinase may replace eGFP expression with
somatodendritic hM3Dq/mCherry expression.
Development Status Phenotyping ongoing
Creation Method knockin
TypeCount
Investigators 1
Experiments 2


Investigators
NameInstitution
Abigail TomlinsonUniversity of Michigan-Ann Arbor


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